Renaissance artist Caravaggio used an early form of photography to project images of his subjects onto a canvas using a noxious concoction of crushed fireflies and white lead.

The 16th century master used modern darkroom techniques to create his masterpieces, more than 200 years before the invention of the camera.

Link:
http://www.telegraph.co.uk/culture/art/4968509/Caravaggio-used-photography-to-create-dramatic-masterpieces.html